Non-Steroidal Anti- Inflammatory Drugs

Non-steroidal anti-inflammatory drugs (NSAIDs) are a medication class that gatherings together medications that diminish torment, diminish fever, and, in higher measurements, diminish irritation. Paracetamol (acetaminophen) is for the most part not considered a NSAID since it has just minimal calming action. It treats torment chiefly by blocking COX-2 for the most part in the focal sensory system, yet very little in whatever is left of the body.

Most NSAIDs repress the action of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), and in this manner the amalgamation of prostaglandins and thromboxanes. It is suspected that restraining COX-2 prompts the calming, pain relieving and antipyretic impacts and that those NSAIDs additionally repressing COX-1, especially headache medicine, may cause gastrointestinal draining and ulcers in expansive measurements.

·         Drug interactions

·         Hypersensitivity reactions

·         Combinational risk

·         Chirality

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